Clinical Trials

Location

Akershus University Hospital

Group/Department

Department of Gastroenterology and Department of Research

Scientific Interests/Background

IBSEN III - Inflammatory Bowel Disease in South Eastern Norway

Specifications

IBSEN III Biobank
Clinical phenotypes (IBD/non-IBD/healthy controls)
Grade of inflammation
Treatment escalation and outcome (i.e. need for biologics and surgery)
Identification of microbiota signatures in IBD phenotypes at diagnosis
Association between microbiota profiles and treatment escalation and outcome (i.e. need for biologics and surgery)

Contact person

Petr Ricanek

Researcher and Consultant

petr.ricanek@medisin.uio.no

Location

OUH Rikshospitalet

Group/Department

Clinical Microbiology and Microbiota Medicine

Scientific Interests/Background

Cardiovascular disease, Infectious diseases, HIV Immunology, Gut microbiota and Development of biomarkers

Materials under Investigation

Blood, biopsies and feces from clinical trials

Specifications

GutHeart
COCOMO

Contact person

Marius Trøseid

Associate Professor

troseid@hotmail.com

Location

OUH Rikshospitalet

Group/Department

Clinical Effectiveness Research Group

Scientific Interests/Background

COLONIZE Donor/Transplantation. Expertise in methodology and conduct of large scale clinical trials

Materials under Investigation

Endoscopy services, tissue sampling and sampling of intestinal contents

Specifications

Currently running a multi center RCT on FMT for primary Clostridioides difficiile-infection (COLONIZE)
Grade of inflammation
Treatment escalation and outcome (i.e. need for biologics and surgery)
Identification of microbiota signatures in IBD phenotypes at diagnosis
Association between microbiota profiles and treatment escalation and outcome (i.e. need for biologics and surgery)

Contact person

Kjetil Kjelstad Garborg

Researcher and Consultant

kjegar@ous-hf.no

Location

OUH Ullevål

Group/Department

Department of Cardiology

Scientific Interests/Background

Acute myocardial infarction and chronic heart disese, including diabetes, heart failure and atrial fibrillation

Specifications

Human intervention studies (Exercise, Omega-3 fatty acids o.a)

Contact person

Ingebjørg Seljeflot

Professor II

uxinlj@ous-hf.no

Location

Lovisenberg Diaconal Hospital

Group/Department

Unger-Vetlesen Institute

Scientific Interests/Background

Internal Medicine, Gastroenterology and Gut Microbiota

Specifications

Experience/track record from several clinical projects concerning gut microbiota, both observational and interventional studies, including evaluating effects of diet and fecal microbiota transplantation
Ongoing projects on SCFAs includes a range of clinical conditions, such as irritable bowel syndrome (IBS), alcohol overconsumption, diabetes mellitus type II, obesity, anorexia nervosa, systemic sclerosis and cerebrovascular disease.
IBSEN III (calprotectin analysis)

Contact person

Jørgen Valeur

jorgen.valeur@lds.no

jorgen.valeur@lds.no

Location

OUH Rikshospitalet

Group/Department

Genomics and Metagenomics in Inflammatory Disorders

Scientific Interests/Background

Primary schlerosing cholangitis
Gut microbiota in inflammatory diseases
Autoimmunity

Materials under Investigation

Blood, biopsies and feces from clinical trials

Specifications

IBSEN III Fecal sample prep and library prep
StopAutoimmunity
ASCT/Microbiome

Contact person

Johannes Hov

Professor

j.e.r.hov@medisin.uio.no

Location

OUH Ullevål

Group/Department

Department of Gastroenterology

Scientific Interests/Background

IBSEN III
Norwegian PI NORDTREAT, the Nordic IBD treatment strategy trial

Specifications

Nordic (No, Sw, Dk, Ice) multicenter randomized trial
Proteomic biomarkers to select patients for top-down anti-TNF treatment
Microbiotics to improve prediction model

Contact person

Marte Lie Høivik

Poejct Leader IBSEN III

marte.lie.hoivik@gmail.com

Location

OUH Rikshopitalet

Group/Department

Department of Dermatology and Department of Pediatric OUS

Materials under Investigation

Skin, amniotic fluid, meconium and fecal samples

Specifications

RCT and observational clinical trial on allergic diseases and other NCDs in Norway and Sweden with 2400 mother-child pairs

Contact person

Eva Maria Rehbinder

Local PI for PreventADALL

e.m.rehbinder@medisin.uio.no

Location

University of Bergen

Group/Department

Department of Clinical Research

Scientific Interests/Background

Nutrition

Materials under Investigation

Feces

Specifications

Microbiome analysis is done in patients taking part in the clinical trial Carbfunc

Contact person

Inge Lindseth

Researcher

inge.lindseth@balderklinikken.no