Clinical Trials
Location
Akershus University Hospital
Group/Department
Department of Gastroenterology and Department of Research
Scientific Interests/Background
IBSEN III - Inflammatory Bowel Disease in South Eastern Norway
Specifications
IBSEN III Biobank
Clinical phenotypes (IBD/non-IBD/healthy controls)
Grade of inflammation
Treatment escalation and outcome (i.e. need for biologics and surgery)
Identification of microbiota signatures in IBD phenotypes at diagnosis
Association between microbiota profiles and treatment escalation and outcome (i.e. need for biologics and surgery)
Location
OUH Rikshospitalet
Group/Department
Clinical Microbiology and Microbiota Medicine
Scientific Interests/Background
Cardiovascular disease, Infectious diseases, HIV Immunology, Gut microbiota and Development of biomarkers
Materials under Investigation
Blood, biopsies and feces from clinical trials
Specifications
GutHeart
COCOMO
Location
OUH Rikshospitalet
Group/Department
Clinical Effectiveness Research Group
Scientific Interests/Background
COLONIZE Donor/Transplantation. Expertise in methodology and conduct of large scale clinical trials
Materials under Investigation
Endoscopy services, tissue sampling and sampling of intestinal contents
Specifications
Currently running a multi center RCT on FMT for primary Clostridioides difficiile-infection (COLONIZE)
Grade of inflammation
Treatment escalation and outcome (i.e. need for biologics and surgery)
Identification of microbiota signatures in IBD phenotypes at diagnosis
Association between microbiota profiles and treatment escalation and outcome (i.e. need for biologics and surgery)
Location
OUH Ullevål
Group/Department
Department of Cardiology
Scientific Interests/Background
Acute myocardial infarction and chronic heart disese, including diabetes, heart failure and atrial fibrillation
Specifications
Human intervention studies (Exercise, Omega-3 fatty acids o.a)
Location
Lovisenberg Diaconal Hospital
Group/Department
Unger-Vetlesen Institute
Scientific Interests/Background
Internal Medicine, Gastroenterology and Gut Microbiota
Specifications
Experience/track record from several clinical projects concerning gut microbiota, both observational and interventional studies, including evaluating effects of diet and fecal microbiota transplantation
Ongoing projects on SCFAs includes a range of clinical conditions, such as irritable bowel syndrome (IBS), alcohol overconsumption, diabetes mellitus type II, obesity, anorexia nervosa, systemic sclerosis and cerebrovascular disease.
IBSEN III (calprotectin analysis)
Location
OUH Rikshospitalet
Group/Department
Genomics and Metagenomics in Inflammatory Disorders
Scientific Interests/Background
Primary schlerosing cholangitis
Gut microbiota in inflammatory diseases
Autoimmunity
Materials under Investigation
Blood, biopsies and feces from clinical trials
Specifications
IBSEN III Fecal sample prep and library prep
StopAutoimmunity
ASCT/Microbiome
Location
OUH Ullevål
Group/Department
Department of Gastroenterology
Scientific Interests/Background
IBSEN III
Norwegian PI NORDTREAT, the Nordic IBD treatment strategy trial
Specifications
Nordic (No, Sw, Dk, Ice) multicenter randomized trial
Proteomic biomarkers to select patients for top-down anti-TNF treatment
Microbiotics to improve prediction model
Location
OUH Rikshopitalet
Group/Department
Department of Dermatology and Department of Pediatric OUS
Materials under Investigation
Skin, amniotic fluid, meconium and fecal samples
Specifications
RCT and observational clinical trial on allergic diseases and other NCDs in Norway and Sweden with 2400 mother-child pairs
Location
University of Bergen
Group/Department
Department of Clinical Research
Scientific Interests/Background
Nutrition
Materials under Investigation
Feces
Specifications
Microbiome analysis is done in patients taking part in the clinical trial Carbfunc